May 2000 Issue

Boom in St. Johns Wort Use Prompts More Drug-Herb Interactions to Surface

Depression is the leading cause of disability. It comes as no surprise then, that sales of St. Johnís wort (Hypericum perforatum), dubbed the herbal antidepressant, have skyrocketed. In one recent year alone, retail sales rose by a staggering 2,800%. This boom has apparently led to an increase in reported cases of interactions between St. Johnís wort and some prescription drugs. Several studies have reported the ability of Hypericum extracts to significantly decrease blood levels of drugs that are metabolized in

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